KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REPS2
All Species:
4.24
Human Site:
S422
Identified Species:
13.33
UniProt:
Q8NFH8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFH8
NP_001074444.1
660
71534
S422
V
P
N
Q
D
V
T
S
D
D
K
Q
A
L
K
Chimpanzee
Pan troglodytes
XP_001138988
583
64793
K361
T
I
N
E
A
L
P
K
D
V
S
E
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001094536
768
83689
D463
P
L
L
V
K
P
S
D
L
S
E
E
N
K
I
Dog
Lupus familis
XP_548876
647
70602
S410
V
P
T
Q
D
V
T
S
D
D
K
Q
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80XA6
521
57731
P298
S
T
V
N
E
S
L
P
K
D
V
S
E
D
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515867
598
66147
Q375
V
V
D
Q
T
L
R
Q
D
L
F
P
G
P
A
Chicken
Gallus gallus
NP_001025977
639
70362
K400
K
D
T
S
K
D
D
K
Q
A
L
K
V
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038521
790
86417
D490
T
K
P
P
E
L
S
D
E
T
K
L
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.1
30.6
90.7
N.A.
69.8
N.A.
N.A.
62.1
66
N.A.
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88
44.4
92.8
N.A.
72.7
N.A.
N.A.
71.2
75.6
N.A.
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
93.3
N.A.
6.6
N.A.
N.A.
20
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
20
93.3
N.A.
13.3
N.A.
N.A.
33.3
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
13
0
0
38
13
38
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
13
0
25
13
13
25
50
38
0
0
13
13
0
% D
% Glu:
0
0
0
13
25
0
0
0
13
0
13
25
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
13
13
0
0
25
0
0
25
13
0
38
13
0
13
25
% K
% Leu:
0
13
13
0
0
38
13
0
13
13
13
13
0
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
13
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
13
25
13
13
0
13
13
13
0
0
0
13
0
25
0
% P
% Gln:
0
0
0
38
0
0
0
13
13
0
0
25
0
0
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
13
0
13
25
25
0
13
13
13
0
13
0
% S
% Thr:
25
13
25
0
13
0
25
0
0
13
0
0
0
0
25
% T
% Val:
38
13
13
13
0
25
0
0
0
13
13
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _